Genetics of Diverticular Disease 

Published by Alicia Ferguson on

Genetics of Diverticular Disease 
What is Diverticular Disease? 

Diverticular disease is a condition that affects the large intestine, a part of the digestive system. Sometimes the inside of the intestine wall can weaken. Pressure to these weak spots can cause small pouches or sacs to bulge from the intestine wall. This can cause inflammation and infection, which can be painful. The exact cause of this pressure and weakness is not fully understood. It is believed to be related to a diet low in fiber and high in processed foods, as well as aging and other factors. 


Symptoms include:

  • Stomach pain
  • Diarrhea 
  • Vomiting
  • Fever 

Doctors may suggest changes in diet or lifestyle to help manage this condition. In some cases, this condition can be treated with antibiotics or surgery to remove the affected part of the intestines. 

How is the research done? 

Researchers have looked into specific genes that are linked to diverticular disease. The researchers are using BioVU resources to study these genes to find out who is more likely to develop diverticular disease and other related health problems. They are also checking other factors that may impact the chances of developing the condition, like race, environment, diet, and exercise. 

What is the importance of this study?  

It is important for medical professionals to know who is at higher risk for having a bad case of this condition. Genetic factors may help explain how mild or severe the condition could get. This will increase our understanding of diverticular diseases and help match the best treatment to each patient.