Gene Regulation Impact on Diseases 

Gene Regulation Impact on Diseases 

What is Gene Regulation? 

The body’s DNA is made of codes or genes that tell the body how to grow and work properly. Gene regulation is like a set of instructions for the DNA to know which genes to use and when to use them. Impairments in these instructions can lead to diseases. It is found that many diseases are caused by code imperfections in our DNA that don’t affect genes directly. These areas of DNA outside of the gene are called non-coding. Non-coding DNA helps organize gene regulating instructions and make sure the genes are working properly. Non-coding DNA can have special parts and codes that can turn these instructions or genes on or off. There is not a lot of information about how these gene regulating areas of DNA work, so it’s hard to figure out how they may be causing diseases. 

How is the research done?

This study wants to look into the impact of non-coding DNA imperfections more. The team wants to find out which codes can make people more likely to get sick or have certain health issues.  They will use BioVU resources to find people with impairments in their non-coding DNA that regulate genes. This will help the team understand how tiny differences in our DNA affect our traits and health. They are also interested in why some codes cause problems while others don’t. This may help to see if they are more likely to have health issues. 

What is the importance of this study? 

This study will look into certain parts of genes to learn more about diseases and how to treat them. This research is important for learning more about gene regulation and how it can cause disease when it does not work as well as it should.