Genetics of an abnormal heart rhythm

Atrial fibrillation, or AF, is the most common type of abnormal heart rhythm. It is often described as an uneven and rapid heart rate. Heart palpitations, shortness of breath and weakness are all symptoms of AF. It affects about 1 in 4 adults in their lifetime. AF is not usually life-threatening. But, it can lead to complications like blood clots in the heart or brain and heart failure. Scientists believe that genetics may play a factor in AF. Researchers at Vanderbilt will use BioVU to look for patients with AF. They will then check for a link between AF and certain gene changes. The goal is to find new gene changes linked to AF. Other researchers around the country are doing similar studies. They will combine information from all the studies in hopes of finding new gene changes linked to AF. This will help doctors better treat AF. It can also help us learn who might be at higher risk for AF.