Genetics of diabetes treatment response

What is Diabetes? 

Diabetes is a condition that happens when your glucose blood sugar is too high. The body has a hard time responding or taking in glucose. This sugar builds up in the blood stream and can lead to health problems.  The cause behind this condition varies but diet and genetics can increase risk. 

Symptoms of this condition can include:

• Increased thirst 
• Frequent urination 
• Blurred vision 
• Numbness or tingling in hands or feet 

Diabetes affects people of all ages and is a lifelong condition. It can be managed with medications and lifestyle changes. Even with medications people with diabetes may still have problems controlling their blood sugar. This might be because of things like not taking their medicine correctly, having side effects, or not being able to afford the medicine. This study wants to learn more about how the medicines used for those with diabetes affect the body based on a person’s genetics. 

How is the research done? 

There are certain genes that help the body take in sugar after eating. This project wants to study the relationship between diabetes medication and those genes. This study believes that genes may explain why some respond better to diabetes medicines than others. They will look at how well certain medicines work and how our genes affect this. The team uses BioVU resources to find those with diabetes and who were prescribed certain medications. The team is studying how well those medicines work and what happens to people who take them for a long time. They also want to know if these medicines are safe for people with high blood pressure. The study team hopes this research can help doctors find better ways to treat people with diabetes. 

What is the importance of this study? 

This research wants to help those with diabetes. This study is important because it looks at genetic impact in treatment response. This can help create better medications and improve health outcomes.