Genetics of endometriosis

Endometriosis occurs when cells that line the uterus start to grow outside the uterus. This tissue acts like normal tissue in the uterus. It gets thicker, breaks down, and bleeds each month. When this happens, it has no way to exit the body. This can cause problems and pain. It can also cause fertility issues. It affects about 1 in 10 women ages 15 to 50. About 1 in 3 women who can’t have children develop this. We usually treat it with drugs or surgery. Risk factors include never giving birth and certain medications. Pelvic surgery scarring and history of pelvic or uterine infections can also increase risk. Early studies suggest certain gene changes may also be a factor. Researchers will use BioVU to look for links between genes and endometriosis. They will also look for specific gene changes in women with this disease. This research may help us better predict who is at risk. It may also lead to better ways to treat or prevent endometriosis.