Genetics of LDL Cholesterol

Published by Luke Morais on

Genetics of LDL Cholesterol


What is LDL Cholesterol?

Most people use “LDL” and “LDL cholesterol” to mean the same thing. LDL cholesterol itself isn’t bad. That’s because cholesterol performs important functions in your body. But too much LDL cholesterol can cause issues.

LDL cholesterol has a reputation for being the “bad cholesterol.” This is because excess LDL cholesterol contributes to plaque buildup in your arteries. This plaque buildup may lead to:

  • Coronary artery disease (CAD)
  • Cerebrovascular disease 
  • Peripheral artery disease (PAD)
  • Aortic aneurysm

There’s a lot you can do to lower your LDL cholesterol. For many people, starting with lifestyle changes can make a big difference. Here are some changes you can make:

  • Eat healthy foods
  • Avoid tobacco use
  • Exercise
  • Maintain a healthy weight
  • Lower your stress levels


How was the study done?

This study aims to identify genes that have variants that affect LDL cholesterol levels in patients. A risk score will be developed for identified genes, and a study will be conducted to find if the gene causes effects in different areas of the body. The study will also investigate if low LDL cholesterol has any clinical effects such as increased risk of diabetes, Alzheimer’s disease, and hemorrhagic stroke. 


What is the importance of this study?

The study aims to learn more about the genes that lower LDL cholesterol levels. By understanding how these genes work, we can better understand the potential risks and benefits they may have for our health. This information can help doctors and researchers develop new treatments and medications to improve our health.