Polygenic risk score creation and testing

Polygenic Risk Score Creation and Testing

What are Polygenic Risk Scores(PRS)? 

Researchers have studied genes and their effect on health for a long time. PRS models use this knowledge to figure out how genes can affect our health. PRS looks at many different genes at once. This can show how the genes work together to impact the presence of different traits or characteristics. Scientists want to see if these models can help predict early on what health conditions people might have in the future.

How is the research done? 

This study believes that our traits can be affected by many genetic factors that work together. They are using BioVU resources to create PRS models that may predict certain traits. They want to study these models to see how useful they are. And if they help predict certain health problems in the future. The research team also wants to know if these models can show if genetic factors that impact our traits may tell us about other parts of our health. 

What is the importance of this study? 

Polygenic risk score models can be developed to study how genes affect our health. Studying genes this way can help predict our risk of getting certain diseases or showing certain traits. This may lead to creating more precise medical care and help to better understand how our genes impact our overall health.