About 1 in 5 adults is very overweight. The only way for most of these people to lose weight is surgery. Not everyone can get the surgery. It costs a lot of money, and there are not enough surgeons. Also, any surgery has a small chance of something going wrong. Read more
Genes for complex diseases like heart disease and diabetes can be hard to find. Scientists think that many genes are involved in these diseases. One common type of study, called a GWAS, can detect some of these genes. But these studies can’t find all of the genes involved. And sometimes, Read more
Genes affect many aspects of a person’s health. But most studies only look at one gene at a time. How different genes work together, or interact, is also important. Scientists have found genes linked to type 2 diabetes. Genes affect a person’s weight or body mass index (BMI). Genes also Read more
Sleep apnea is when a person stops breathing while they are sleeping. These pauses in breathing can disturb sleep. Many people with sleep apnea also snore. These things can cause a person to be very sleepy during the day. People with sleep apnea often have high blood pressure, heart disease, Read more
Cushing’s syndrome happens when the body has too much of the hormone cortisol. The most obvious sign of Cushing’s syndrome is rapid weight gain around the belly. The condition can lead to diabetes and high blood pressure. If not treated, Cushing’s syndrome can be deadly. There are some medicines to Read more
Some drugs can damage the kidneys. Within 2 days, this can cause your kidneys to stop working right. This is called acute kidney injury (AKI). Diabetic patients are specifically prone to kidney injury. There is no way to know which patients will get AKI after taking these drugs. This project’s Read more
In type 2 diabetes, blood sugar levels are too high. Over time, high blood sugar can damage the kidneys, heart, eyes, nerves and other organs. Many people with diabetes take the drug metformin to help control blood sugar. But the drug works better for some people than others. Drug transporters Read more